Publications
2025
Breves S., Di Giammartino D.C., Nicholson J., Polyzos A., Fine H., Apostolou E.
Three-dimensional regulatory hubs support oncogenic programs in glioblastoma
Molecular Cell
2024
Murphy D., Salataj E., Di Giammartino D.C., Rodriguez-Hernaez J., Kloetgen A., Garg V., Char E., Uyehara C.M., Ee L.-S., Lee U.J., Stadtfeld M., Hadjantonakis A.-K., Tsirigos A., Polyzos A., Apostolou E.
3D Enhancer–promoter networks provide predictive features for gene expression and coregulation in early embryonic lineages
Nature Structural and Molecular Biology, vol. 31, (no. 1), pp. 125-140
2022
He Y., Kim I.-K., Bian J., Polyzos A., Di Giammartino D.C., Zhang Y.-W., Luo J., Hernandez M.O., Kedei N., Cam M., Borczuk A.C., Lee T., Han Y., Conner E.A., Wong M., Tillo D.C., Umemura S., Chen V., Ruan L., White J.B., Miranda I.C., Awasthi P.P., Altorki N.K., Divakar P., Elemento O., Apostolou E., Giaccone G.
A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation
Journal of Thoracic Oncology, vol. 17, (no. 12), pp. 1375-1386
2021
Pelham-Webb B., Polyzos A., Wojenski L., Kloetgen A., Li J., Di Giammartino D.C., Sakellaropoulos T., Tsirigos A., Core L., Apostolou E.
H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization
Molecular Cell, vol. 81, (no. 8), pp. 1732-1748.e8
2021
Doane A.S., Chu C.-S., Di Giammartino D.C., Rivas M.A., Hellmuth J.C., Jiang Y., Yusufova N., Alonso A., Roeder R.G., Apostolou E., Melnick A.M., Elemento O.
OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity
Nature Immunology, vol. 22, (no. 10), pp. 1327-1340
2020
Di Giammartino D.C., Polyzos A., Apostolou E.
Transcription factors: building hubs in the 3D space
Cell Cycle, vol. 19, (no. 19), pp. 2395-2410
2019
Lhoumaud P., Sethia G., Izzo F., Sakellaropoulos T., Snetkova V., Vidal S., Badri S., Cornwell M., Di Giammartino D.C., Kim K.-T., Apostolou E., Stadtfeld M., Landau D.A., Skok J.
EpiMethylTag: Simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation
Genome Biology, vol. 20, (no. 1)
2019
Di Giammartino D.C., Kloetgen A., Polyzos A., Liu Y., Kim D., Murphy D., Abuhashem A., Cavaliere P., Aronson B., Shah V., Dephoure N., Stadtfeld M., Tsirigos A., Apostolou E.
KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks
Nature Cell Biology, vol. 21, (no. 10), pp. 1179-1190
2019
Seruggia D., Oti M., Tripathi P., Canver M.C., LeBlanc L., Di Giammartino D.C., Bullen M.J., Nefzger C.M., Sun Y.B.Y., Farouni R., Polo J.M., Pinello L., Apostolou E., Kim J., Orkin S.H., Das P.P.
TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network
Molecular Cell, vol. 74, (no. 6), pp. 1148-1163.e7
2017
Liu Y., Pelham-Webb B., Di Giammartino D.C., Li J., Kim D., Kita K., Saiz N., Garg V., Doane A., Giannakakou P., Hadjantonakis A.-K., Elemento O., Apostolou E.
Widespread Mitotic Bookmarking by Histone Marks and Transcription Factors in Pluripotent Stem Cells
Cell Reports, vol. 19, (no. 7), pp. 1283-1293
2016
Di Giammartino D.C., Apostolou E.
The Chromatin Signature of Pluripotency: Establishment and Maintenance
Current Stem Cell Reports, vol. 2, (no. 3), pp. 255-262
2014
Di Giammartino D.C., Manley J.L.
New links between mRNA polyadenylation and diverse nuclear pathways
Molecules and Cells, vol. 37, (no. 9), pp. 644-649
2014
Di Giammartino D.C., Li W., Ogami K., Yashinskie J.J., Hoque M., Tian B., Manley J.L.
RBBP6 isoforms regulate the human polyadenylation machinery and modulate expression of mRNAs with AU-rich 39 UTRs
Genes and Development, vol. 28, (no. 20), pp. 2248-2260
2013
Chan A.-L., Grossman T., Zuckerman V., Campigli Di Giammartino D., Moshel O., Scheffner M., Monahan B., Pilling P., Jiang Y.-H., Haupt S., Schueler-Furman O., Haupt Y.
C-Abl phosphorylates E6AP and regulates its E3 ubiquitin ligase activity
Biochemistry, vol. 52, (no. 18), pp. 3119-3129
2013
Di Giammartino D.C., Shi Y., Manley J.L.
PARP1 Represses PAP and Inhibits Polyadenylation during Heat Shock
Molecular Cell, vol. 49, (no. 1), pp. 7-17